Research

 

For over forty years Digitimer have manufactured and distributed a wide range of quality electrophysiology equipment, including biological amplifiers, stimulators and other products, used by biomedical researchers worldwide.  We offer a wide range of in vitro and in vivo electrophysiology equipment and currently represent eight companies. Please use the drop-down menus or the product links above to discover more about equipment you may be interested in.

We offer a range of data acquisition (DAQ) interfaces from HEKA, including the ITC-18 formerly manufactured by Instrutech and several from National Instruments. These DAQ systems are predominantly designed for high speed electrophysiology data acquisition, including voltage and patch clamp recording.  The NI boards we offer have been chosen for compatibility with QtracW, a specialist threshold tracking software for human nerve excitability research.

aquisition-interfaces

HEKA LIH 8+8
HEKA ITC-18
HEKA PCI & USB Host Interfaces
NI USB-6221-BNC
NI USB-6251-BNC

Digitimer manufacture and supply biological amplifiers suitable for many biomedical research applications. Our NeuroLog System range includes biological amplifier modules suitable for intracellular recording, extracellular recording, isolated, multi-channel recording and transducer (force or pressure) monitoring.

amplifier

Digitimer NeuroLog System
Digitmer D360 Patient Amplifier
Digitimer D440 2/4 Isolated Amplifier
HEKA EPC10 Patch Clamp Amplifier
HEKA EPC10/n Patch Clamp Amplifiers
HEKA EPC800 Patch Clamp Amplifier
HEKA iTEV90 Voltage Clamp Amplifier

Techniques involving manipulation under microscopic control are vibration sensitive, therefore, it is necessary to invest in a good anti-vibration table as the first stage when assembling a new electrophysiology rig.

anti-vibration-equipment

ThorLabs ScienceDesks & Faraday Cages
Narishige ITS Anti-vibration Platforms
Narishige Double Magnet System
Narishige SBP-2 Baseplate

Our range of pneumatic cell injectors includes the PLI-10A and PLI-100A Pico-injectors from Warner Instruments and syringe based injectors from Narishige.

cell-injector

PLI-100A Pico-injector
PLI-10 Pico-injector
Narishige IM-11-2
Narishige IM-9B
Narishige IM-9C
Narishige IM-6
Narishige IM-400
Syringes & Injection Accessories

Digitimer offer 19″ equipment racks which can be floor-standing or bench-mounted, providing you with flexible solutions for equipment positioning.

research-equipment-bench_rack

Bench-top 19″ Equipment Rack
Floor-standing 19″ Equipment Rack
D121-11 Mounting Frame

Signals recorded using biological sensors and other high impedance devices are often contaminated with 50 or 60 Hz noise corrupting the content of these signals and degrading the quality of subsequent data analysis. The Hum Bug noise eliminator offers a novel solution by subtracting mains frequency interference from your signal in realtime without filtering.

Humbug-noise-eliminator-digitimer

Representing the AutoMate Scientific, Harvard and Scientific Systems Design, we supply chambers and temperature controlled micro-incubators for many applications.

Incubators-chambers-digitimer

AutoMate Perfusion Chambers
Medical Systems Micro-incubators
SSD Brain Slice Chambers

Digitimer manufactures the D380 Iontophoretic Dye Marker and supplies the NeuroPhore BH-2 system which is a modular drug delivery system from Harvard.

Iontophoreti-devices-digitimer

D380 Dye Marker
BH-2 NeuroPhore System

Narishige have a reputation for manufacturing high quality manipulation equipment used in many fields. We supply the full range of Narishige coarse and fine manipulators for electrophysiology and injection.

Manipulators-digitimer

Electrophysiology System Manipulators
Injection System Manipulators
“YOU” Compact Manipulators
Stereotaxic System Manipulators
Chronic Manipulators
Manipulator Microscope Adaptors
Accessories & Consumables

Digital Storage Oscilloscopes allow electrophysiologists to examine the signal of interest in high resolution without having to reach for the computer. Oscilloscopes can also be very useful for verification and testing of other equipment, as well as troubleshooting problems or issues related to electrical interference.  Digitimer offers the same Tektronix oscilloscopes that our engineers use every day.

Oscilloscopes-digitimer

TDS2000C Tektronix Oscilloscope

Automate Scientific design and manufacture a range of automated perfusion systems for in vitro drug application or gravity fed in vivo fixation devices.  Products include heated and pressurised perfusion systems and a range of compatible accessories.

Perfusion-systems-digitimer

Standard & Pressurized Perfusion
SmartSquirt Micro-Perfusion
In Vivo Perfusion (Fixation)
ThermoClamp – Heated Perfusion

Digitimer supply a large range of pipette fabrication tools and accessories (such as heater elements and glass) provided by Narishige and HEKA Elektronik, two highly respected manufacturers of electrophysiological equipment.

Pipette-pullers-digitimer

Pipette/Microelectrode Pullers
Microforges & Grinders
Replacement Parts
Capillary Glass

The DG2A has been designed to provide you with a simple battery powered controller of repetitive stimulation and operates in several modes. It is also useful for determining effective refractory period through use of a second, delayed pulse.  For more complex timing protocols, such as repetitive bursts, please refer to the the timing and pulse generating modules within the NeuroLog System.

Programmers-timers-digitimer

DG2A Train/Delay Generator
Digitimer NeuroLog System

Digitimer recommends Thurlby Thandar function generators for use with our D179 Performance Checker. The D179 is capable of attenuating a calibrated output from one of the function generators below, so it can be fed into a clinical amplifier system.  The actual amplifier gain can then be verified against the expected gain, as an amplifier performance check.

Signal-generators-digitimer

TG315 3MHz Function Generator
TG1010A 10MHz Function Generator

Digitimer supply a range of software packages for use with many of our hardware products from AutoMate Scientific (ValveBank) and HEKA Elektronik (patch/voltage clamp amplifiers).  We are also the sole source of the specialist QtracW nerve excitability/threshold tracking software.
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