Life Science Research
For over forty years Digitimer have designed, manufactured and distributed a wide range of quality electrophysiology equipment, including biological amplifiers, stimulators and other products, used by biomedical researchers worldwide. We offer a variety of in vitro and in vivo electrophysiology equipment to complement our own products and currently represent eight respected life science research instrument manufacturers. Please use the drop-down menu above or the product/category links below to discover more about the equipment you may be interested in.
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Acquisition Interfaces
We offer a range of data acquisition (DAQ) interfaces including some from National Instruments, which are vital components within QtracW-based threshold-tracking nerve, muscle and cortical excitability systems.Subcategories / ProductsAmplifiers
As leaders in our field, we manufacture and supply a wide range of biological amplifiers. These are designed for use in biomedical research and clinical environments. Our research amplifiers are suitable for intracellular/extracellular recording, multi-channel recording and transducer monitoring. We also have a range of isolated amplifiers, some medically approved, for human EMG, EEG and EP recording.These are all high-specification, quality devices – yet they’re still available for a competitive price. Whatever the nature of your latest research study, we’re confident we have the ideal amplifier to meet your needs. So, why not take a look through our full collection? Further information on each device can be found in our product brochure. But if you have any questions, or need help choosing the ideal amplifier, please don’t hesitate to get in touch. [vc_tta_accordion active_section="0" collapsible_all="true"][vc_tta_section title="Why shop with us for amplifiers?" tab_id="1645615373920-f10d4f90-d20e"][vc_column_text]Digitimer is a leading designer and manufacturer of scientific devices, particularly for use in biomedical research. In fact, our amplifiers are now used in studies all over the world.Since our establishment, we’ve honed our skills in this area and developed a series of cutting-edge biological and isolated amplifiers, which fully meet the needs of specific users. Nevertheless, we still like to push ourselves. Working in collaboration with universities and hospitals, we’re committed to product development and continuously strive to create new, innovative products for our clients.
One of our latest developments includes the D360R multi-channel isolated research amplifier. This is based on our 8-channel D360 isolated patient amplifier, but is the 4-channel research equivalent: compact, cost-effective, yet highly specified and designed for use in EMG, EEG and EP recording.
All products in our amplifier range are CE certified. They’re available for a very competitive price and, as a team of specialists, we like to offer our clients an excellent pre- and post-sales service.[/vc_column_text][/vc_tta_section][vc_tta_section title="Which is the right amplifier for my research?" tab_id="1645615373927-6ff4f2e6-993e"][vc_column_text]Whilst many of our amplifiers are designed to be ‘general purpose’, each one has features that make it more suitable for a particular type of recording – and it’s worth taking this into consideration when placing your order.
Detailed information can be found under each product listing and in our product brochure. Our NeuroLog System amplifier modules and SPP-100 Extracellular Amplifier are intended for a range of in vitro and animal research applications. For our amplifiers intended for human use, we have a blog that focuses specifically on how to select an appropriate isolated amplifier.
These resources should help you to narrow down the options and identify the most appropriate device. But if you’re still unsure, please feel free to give us a call. Once we know a bit more about the intended application and requirements of your research, our in-house experts can guide you through the selection process and advise on the most suitable amplifier for your needs.[/vc_column_text][/vc_tta_section][vc_tta_section title="How much do amplifiers cost?" tab_id="1645615507131-9c13d892-be2c"][vc_column_text]This varies depending on the type of amplifier that you require.
The manufacturer’s Net List Price for each device is displayed below. But it’s important to be aware, this excludes UK VAT and shipping costs. And if you live outside of the UK, the price you pay for a particular amplifier will depend on how Digitimer Ltd is represented and supported in your country.
In most cases, the best option is to submit a request for a quote. Just add the amplifier to your ‘quote list’ and provide a few details, including how you intend to use it. We’ll respond as soon as possible with application-specific advice and a tailored quote for your needs.
Alternatively, you’re welcome to call us at any time. We’re always happy to help and will gladly talk you through the biological and isolated amplifiers available and their associated costs.[/vc_column_text][/vc_tta_section][/vc_tta_accordion]
Subcategories / ProductsAnti Vibration Equipment
Techniques involving manipulation under microscopic control are vibration sensitive, therefore, it is necessary to invest in a good anti-vibration table as the first stage when assembling a new electrophysiology rig.Subcategories / ProductsCell Injectors
Our range of cell injectors includes the PLI-10A and PLI-100A Pico-injectors from Warner Instruments, the electric IM-400, pneumatic IM-11-2 and syringe-based IMS-20 injectors from Narishige.Subcategories / ProductsIncubators & Chambers
With products from Scientific Systems Design (SSD) and AutoMate Scientific, we supply a vast array of free-standing chambers for slices in interface and submerged recording modes as well as stage mounted versions for slice and cell culture preparations under ambient and temperature-controlled conditions. We also provide brain slice keepers for pre-incubation of brain and other tissue slices prior to electrophysiological recording or imaging.Subcategories / ProductsIontophoretic Devices
Digitimer manufactures the D380 Iontophoretic Dye Marker, useful for neuroanatomical dye labelling when a current injecting amplifier is not available.Subcategories / ProductsMains Noise Eliminators
Signals recorded using biological amplifiers and other high impedance devices are often contaminated with 50 or 60 Hz mains noise, leading to corruption of the content of these electrophysiological signals and a degradation of the quality of subsequent data analysis. Digitimer now manufactures the original single channel Humbug alongside our new multi-channel D400 Mains Noise Eliminator, available in 2,4 and 8 channel variants for effective removal of mains interference without signal distortion.Subcategories / ProductsManipulators
Narishige have a reputation for manufacturing high quality manipulation equipment used in many fields. We supply the full range of Narishige coarse and fine manipulators for electrophysiology and injection.Subcategories / ProductsMED64 Multi-Electrode Array Systems
Digitimer represents Alpha MED Science Inc. and their range of multielectrode array (MEA) systems. Developed from the Panasonic MED64 system, Alpha MED now manufacture the most sensitive in vitro MEA systems available for extracellular electrophysiology.Subcategories / ProductsPerfusion Equipment
Automate Scientific design and manufacture a range of automated perfusion equipment for in vitro drug application or gravity fed in vivo fixation devices. Products include heated and pressurised perfusion systems and a range of compatible accessories.Subcategories / ProductsPipette Fabrication
Digitimer supplies a wide range of pipette fabrication tools and accessories (such as heater elements and glass) designed and manufactured by Narishige. Products include vertical pipette pullers for patch-clamp and micro-injection; fire-polishers (microforges) and electrode grinders.Subcategories / ProductsProgrammers & Timers
Digitimer offers two hardware solutions for the delivery of repetitive trigger pulses to control our range of electrical stimulators or other devices. The DG2A Train/Delay Generator is a simple, battery-powered trigger source, with several operating modes. The DG2A is also useful for determining effective refractory period through use of a delayed second pulse. More advanced timing protocols can be developed using our modular NeuroLog System, which can operate as a multi-purpose pulse generator. Using appropriate modules, complex pulse and/or TTL trigger patterns can be produced.Subcategories / ProductsSignal Generators
Digitimer recommends Thurlby Thandar function generators for use with our D179 Performance Checker. The D179 is capable of attenuating a calibrated output from one of the function generators below, so it can be fed into a clinical amplifier system.Subcategories / ProductsSoftware
Digitimer supplies a range of software packages for use with many of our hardware products, incliding AutoMate Scientific (ValveBank). We are also the sole source of the specialist QtracW nerve excitability/threshold tracking software and QTMS extension.Subcategories / ProductsStimulators
As a leading supplier of products for life science and neurophysiological research, we manufacture and stock a diverse range of stimulators – including constant current and constant voltage stimulators, low-noise stimulus isolators, and multi-channel stimulators for human and clinical use.These are all innovative, high-quality devices, available at very competitive prices. Whatever the nature of your latest research study, we’re almost certain to have a stimulator that meets your needs.Browse our full collection today, and if you have any questions – or would like tailored advice on the best electric stimulator for your application – please don’t hesitate to contact our experts. [vc_tta_accordion active_section="0" collapsible_all="true"][vc_tta_section title="Why shop with us for stimulators?" tab_id="1645615373920-f10d4f90-d20e"][vc_column_text]Digitimer Ltd has an international reputation for high-quality electrical stimulators. Our devices are used all over the world for electrophysiological applications, both in clinical and biomedical research areas, and we always strive to push the boundaries with our product range. Over the last 40 years, we have honed our skills in this area and created a fantastic selection of stimulators to meet our clients’ needs. Nevertheless, we’re still committed to product development and continuously work alongside universities and hospitals to develop new innovative devices. The latest of which includes the DS8R – a multi-mode constant current stimulator, designed for human research and regarded as the ‘next generation’ of muscle and nerve stimulation. All of our stimulators are CE certified and either meet or exceed required standards. As an ISO 13485 certified manufacturer, we have extensive experience within the area of medical device design, development and manufacture. Furthermore, client satisfaction is at the heart of everything we do. Our prices are competitive and we pride ourselves on our excellent pre- and post-sales service.[/vc_column_text][/vc_tta_section][vc_tta_section title="Which stimulator is right for me?" tab_id="1645615373927-6ff4f2e6-993e"][vc_column_text] Due to the wide range and complexity of devices now available, we appreciate that choosing the right medical or human research stimulator for your needs may not be the easiest decision. We always aim to make our stimulators as general-purpose as possible. But inevitably, some devices are better suited to certain applications than others. And the best device for you will depend on several factors, including the nature of your research, how/where you intend to use it and more. When selecting an electric stimulator, some of the most important things to consider include:- Output current range
- Output resolution and accuracy
- Compliance voltage
- Pulse duration
- Output pulse shape
- Polarity, biphasic or charge-balanced output
- Hardware and software control methods
Subcategories / ProductsDS2A Isolated Voltage Stimulator
DS3 Isolated Current Stimulator
DS4 Bi-Phasic Current Stimulator
NL800A Current Stimulus Isolator
DS5 Isolated Bipolar Constant Current Stimulator
DS7A & DS7AH High Voltage Constant Current Stimulators
DS7R Constant Current Research Stimulator
DS8R Biphasic Constant Current Stimulator
D330 MultiStim System
The modular MultiStim System has been designed for use in laboratories where several in vitro preparations in tissue baths or cell culture wells require field stimulation from a low-impedance source. The system uses a common timing waveform for each channel but different stabilised stimuli to each preparation. The system includes modules for constant voltage and constant current stimulation.High Current or Voltage Stimulation
The system provides a choice of either constant voltage stimulation (up to 100V at 1A - D333H) or constant current stimulation (up to 500mA from a 100V source - D343).Built-in Stimulus Monitoring
The D335 - Meter can be fitted into the system to allow precise voltage or current monitoring.Internal or External Timing Capabilities
A selection of timing modules are available to generate pulses, variable in frequency and width, which can be controlled as bursts using a gating waveform, variable in repetition rate and duration or pulse count. Sockets are fitted to allow full external control and synchronisation if required.Bench Top or Rack Mountable
The D330-MultiStim System rack/case is available in a 19" rack-mountable unit - D337, that can house the Gated Pulse Train Generators and up to ten stimulation channels.Modular Solution for Changing Requirements
The modularity of the system allows a system to be extended or split between smaller units for two sites.Subcategories / Products
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PE-22 Micropipette Puller
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AP-12L AP-12N Patch Clamp Headstage Holders
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QtracW Threshold Tracking Software
£2,000.00 – £4,000.00 exc. VAT View This product has multiple variants. The options may be chosen on the product page -
QTMS Transcranial Magnetic Stimulation Software
£2,880.00 exc. VAT View -
AutoMate Easycode Software
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B-8B B-8C Ball Joints
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B-9 Ball Joint
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BE 8 Manipulator with Ball Joint
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BSC1 Brain Slice Heated Chamber
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BSC1-2 Two Channel Brain Slice Heated Chamber
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BSC2 Brain Slice Heated Interface Chamber
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BSC2-2 Dual Channel Heated Interface Chamber
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BSC3 Brain Slice Heated Chamber (2,3,4 or 6 Ch.)
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CA-6 Head Holding Adaptor (for Common Marmosets)
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CF-10 Chamber Frame (for Mice)
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CFR-1 Chamber Frame (for Rats)
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CFR-2 Chamber Frame (for Rats)
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Chronic Manipulators
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CP Chamber Plate (for Mice)
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CP-1 Chamber Plate (for Mice)
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CP-2 Chamber Plate (for Mice)
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D331AT Sync & Gate Module
£865.00 exc. VAT View -
D332T Pulse Module
£630.00 exc. VAT View -
D333H DualStim Module
£750.00 exc. VAT View -
D334B Sync Module
£470.00 exc. VAT View -
D335 Meter Module
£750.00 exc. VAT View -
D337 MultiStim Case & Power Supply
£1,495.00 exc. VAT View -
D340 Count & Delay Module
£590.00 exc. VAT View -
D341A Sync & Train Module
£865.00 exc. VAT View -
D342 Dual Bistim Module
£500.00 exc. VAT View -
D343 DualStim Module (Constant Current)
£750.00 exc. VAT View -
D344A Remote Module
£500.00 exc. VAT View -
D360 8 Channel Patient Amplifier
£11,860.00 exc. VAT View -
D360R Multi-channel Isolated Research Amplifier/Filter
£5,995.00 exc. VAT View -
D380 Iontophoretic Dye Marker
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D440 2 or 4 Channel Isolated EMG Amplifier
£3,000.00 – £4,200.00 exc. VAT View This product has multiple variants. The options may be chosen on the product page -
D400 Multi-channel 50Hz/60Hz Mains Noise Eliminator
£2,395.00 – £4,295.00 exc. VAT View This product has multiple variants. The options may be chosen on the product page -
DG2A Train Delay Generator
£640.00 exc. VAT View -
SPP-100 Extracellular Amplifier/Filter
£2,750.00 exc. VAT View -
DM-OH-2 Compact Controller (for DM System)
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DM-OR1-2 Drum Controller (for DM System)
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DS2A Isolated Voltage Stimulator
£877.00 exc. VAT View -
DS3 Isolated Current Stimulator
£1,002.00 exc. VAT View -
DS4 Bi-Phasic Current Stimulator
£1,744.00 exc. VAT View -
D121-11 Mounting Frame
£75.00 exc. VAT View -
NL800A Current Stimulus Isolator
£442.00 exc. VAT View -
DS5 Isolated Bipolar Constant Current Stimulator
£6,849.00 exc. VAT View -
DS7A & DS7AH High Voltage Constant Current Stimulators
£3,701.00 – £3,846.00 exc. VAT View This product has multiple variants. The options may be chosen on the product page -
DS7R Constant Current Research Stimulator
£3,662.00 exc. VAT View -
DS8R Biphasic Constant Current Stimulator
£8,555.00 exc. VAT View -
D185 MultiPulse Transcranial Cortical Stimulator
£6,604.00 exc. VAT View -
EB-3A Ear Bars (for Rats)
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EB-3B Ear Bars (for Mice)
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EB-4N Auxiliary Ear Bar (for Rats)
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EB-5N Auxiliary Ear Bar (for Mice)
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EB-6 Ear Bars (for Mice)
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MF2 Microforge
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Electrode Holders and Pipette Holders
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Electrophysiology System Manipulators
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GJ 1 Magnetic Stand
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GJ 12 Magnetic Stand – Thin-type
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GJ 8 Magnetic Stand
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GJD 1 Magnetic Bridge Stand
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Glass Capillary G-1/G-1.2/G-1.5/G-2/G-3
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Glass Capillary G-100/G-100L
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Glass Capillary GC-1/GC-1.2/GC-1.5
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Glass Capillary GD-1/GD-1.2/GD-1.5/GD-2
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Glass Capillary GDC-1/GDC-1.2/GDC-1.5
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Glass Rod G-1000
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GM-3 Anesthetic Mask (for Rats)
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GM-4 Anesthetic Mask (for Mice)
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Hum Bug Noise Eliminator
£1,493.00 exc. VAT View -
IMS-20 Motorized Stereotaxic Microinjector
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IMS-30 Motorized Stereotaxic Microinjector
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IMS-3 Stereotaxic Microinjector
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In Vivo Fixation System
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Multi-channel Perfusion Pencil
£322.00 exc. VAT View This product has multiple variants. The options may be chosen on the product page -
Perfusion Pencil Replacement Tips (100µm, 250µm, 360µm)
£52.00 exc. VAT View This product has multiple variants. The options may be chosen on the product page -
Injection System Manipulators
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IP Iron Plate
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M 152 Manipulator
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M 3333 Micromanipulator
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MA-1 Electrode Position Calibrator
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MA-2 Micromanipulator Stand
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MA-6N/MA-6N1 Head Holding Adaptor (for Mice)
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MAG-1 Simple Head Holder Plate (for Mice)
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MAG-2 Head Holding Device (with Angle Adjuster / for Mice)
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MAG-3 Head Holding Device (with Angle Adjuster / for Mice)
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Manipulator Microscope Adaptors for Electrophysiology
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Manipulator Microscope Adaptors for Injection
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MC Membrane Stage Chamber
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TCKG Nerve/Muscle/Tissue Chamber
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MED64 Basic MEA System
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MED64 Allegro MEA System
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MED64 Quad II MEA System
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MED64 Plex 4/8 MEA System
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MED64 Probes
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MED64 Mobius Software – Acquisition & Analysis
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MED64 Presto MEA System
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Microforge Lenses & Eyepieces
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EG-45 Microgrinder
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EG-402 Microgrinder
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MHW-103 Three Axis Water Hydraulic Micromanipulator
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MHW-3 Three Axis Water Hydraulic Micromanipulator
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MHW-4 Single Axis Water Hydraulic Micromanipulator
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MHW-A Tilting Adaptor
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MM 3 Micromanipulator
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MMN-1 Coarse Manipulator
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MMO 203 Three-axis Oil Hydraulic Micromanipulator
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MMO 220A Single-axis Oil Hydraulic Micromanipulator
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MN 151 Joystick Micromanipulator
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MN 153 Micromanipulator
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MO 10 One-axis Oil Hydraulic Micromanipulator
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MO 8HL Long Holder for MO 10
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MDO-974 Oil Hydraulic-Motorized Hybrid Micromanipulator (with Closed Chamber)
£6,996.00 exc. VAT View -
MDO-974A Oil Hydraulic-Motorized Hybrid Micromanipulator (with Open Chamber)
£6,996.00 exc. VAT View -
MO-97 Oil Hydraulic Micromanipulator
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MP 2 Tilting Micromanipulator
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MS1 Microscope Stage Chamber
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MS2 Microscope Stage Chamber
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MS3 Microscope Stage Chamber
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MS4 Microscope Stage Chamber
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MS5 Coverslip Microscope Stage Chamber
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BSK1 Brain Slice Keeper
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BSK2 Low Volume Brain Slice Keeper
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BSK4 Submerged Brain Slice Keeper (4 well)
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BSK5-2 Two Well Interface Brain Slice Keeper
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BSK6 Multi-well Low Volume Brain Slice Keeper
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BSK12 Submerged Multi-well Brain Slice Keeper
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BST Brain Slice Transporter
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MX 2 Micromanipulator
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Narishige IM-11-2 Pneumatic Microinjector
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Narishige IM-21 Oil Injector
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Narishige IM-400 Electric Microinjector
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Narishige ITS Anti-Vibration Platforms
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Narishige SBP-2 Baseplate
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National Instruments USB-6341-BNC
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NL100AK AC Pre-Amplifier Headstage
£405.00 exc. VAT View -
NL100RK Stimulus Control Headstage
£1,285.00 exc. VAT View -
NL102G DC Pre Amplifier
£2,003.00 exc. VAT View -
NL104A AC Preamplifier
£872.00 exc. VAT View -
NL106 AC/DC Amplifier
£872.00 exc. VAT View -
NL108A Pressure Amplifier
£776.00 exc. VAT View -
NL109 Bridge Amplifier
£845.00 exc. VAT View -
NL120S Audio Amplifier
£440.00 exc. VAT View -
NL820A Isolation Amplifier
£1,482.00 exc. VAT View -
NL844 AC Pre-amplifier (4Ch.)
£2,373.00 exc. VAT View -
NMN 25 Micromanipulator
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NMN-21 Micromanipulator
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NMN-A Tilting Stand
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NR-12 Rotating Adjustable Clamp
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NR-35 Rotating Adjustable Clamp
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Oocyte Perfusion Chamber (OPC-1)
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P-1A & P-1B Height Adjustment Plates
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P-1A & P1-B Height Adjustment Plates
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PC-100 Micropipette Puller
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Petri-dish Perfusion Chamber (PCP-1)
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PTC03 Low Noise Proportional Temperature Controller
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PTC05 Low Noise Proportional Temperature Controller
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PTC04 Proportional Temperature Controller
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MHC01 Mini Heating/Cooling Module
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MH02 Mini Heating Module
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Quickstage Microscope Stage Chambers
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RA-6N Head Holding Adaptor (for Rats)
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Microforge Heater Wire
£65.00 – £101.00 exc. VAT View This product has multiple variants. The options may be chosen on the product page -
Pipette Puller Heaters
£65.00 – £225.00 exc. VAT View This product has multiple variants. The options may be chosen on the product page -
SG-3N Head Holder (for Rats)
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SGM-3 Head Holder (for Rats)
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SGM-4 Head Holder (for Mice)
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SGP-3 Head Holder (for Rats)
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SGP-4 Head Holder (for Mice)
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SHC-1 Cannula Holder
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SM-11 Stereotaxic Micromanipulator
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SM-11-HT Stereotaxic Micromanipulator
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SM-11A Attachment
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SM-15A-2 Attachment
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SM-15B Holder Attachment
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SM-15C Attachment
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SM-15HE Multiuse Holder
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SM-15M-2 Substage
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MD-DCE-7 Connecting Cable 7m (for MD system)
£259.00 exc. VAT View -
MD-OH-1 Compact Controller
£535.00 exc. VAT View -
MDO-84 One-axis Oil Hydraulic-Motorized Hybrid Micromanipulator
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MDS-1 One-axis Motorized Stereotaxic Micromanipulator
£4,103.00 exc. VAT View -
SM-15R-L Stereotaxic Micromanipulator
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SM-25A Stereotaxic Micromanipulator (Thin-type, Coarse/Fine Drive)
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SM-25C Stereotaxic Micromanipulator (Thin-type, One-axis, Oil Hydraulic System)
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SM-25HE Multiuse Holder
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SmartSquirt Micro Perfusion Systems
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SMM-100 Stereotaxic Micromanipulator
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SMM-100C Stereotaxic Micromanipulator
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SMM-200C Stereotaxic Micromanipulator
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SMM-200 Stereotaxic Micromanipulator
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SMM-A Attachment
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SMM-HA Holder for Neural Probes
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SMM-HB Holder for Neural Probes
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SMM-HC Cannula Holder
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SMM-HD Multiuse Holder
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SMM-HE Multiuse Holder
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SR-10AR Head Holding Device (for Chronic Experiments on Rats)
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SR-10R-HT Stereotaxic Instruments (for Chronic Experiments on Rats)
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SR-5B Base Plate
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SR-5C-HT Stereotaxic Instruments (for Common Marmosets)
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SR-5M-HT/SR-5M1-HT Stereotaxic Instruments (for Mice)
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SR-5R-HT Stereotaxic Instruments (for Rats)
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SR-6B Base Plate
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SR-6C-HT Stereotaxic Instruments (for Common Marmosets)
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SR-6M-HT/SR-6M1-HT Stereotaxic Instruments (for Mice)
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SR-6R-HT Stereotaxic Instruments (for Rats)
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SR-9AM Head Holding Device (for Chronic Experiments on Mice)
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SR-9M-HT Stereotaxic Instruments (for Chronic Experiments on Mice)
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SR-A Plate
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SRP-5R-HT2 Stereotaxic Instruments (for Rats/MRI-compatible)
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SRP-AM2 Head Holding Device (for Mice/MRI-compatible)
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SRP-AR2 Head Holding Device (for Rats/MRI-compatible)
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SRS-A Compact Head Holding Device (for Mice/Newborn Rats)
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Standard & Pressurised Perfusion Systems
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Stereotaxic Systems
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STS-A Compact Spinal Cord Clamps (for Mice/Newborn Rats)
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STS-B Compact Spinal Cord Clamps (for Rats)
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Syringes & Injection Accessories
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TG315 3MHz Function Generator
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ThermoClamp Heated Perfusion
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U 3C Compact Manipulator
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UM 3C & UMM 3C Manipulators
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UMM 3FC Micromanipulator
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UM-1FC Manipulator
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UM-1PFC Manipulator
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UPN 1 Pipette Holder
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UPN-10 Pipette Holder
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UPN-20 Pipette Holder
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UPN-B Ball Joint
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UPN-C Pipette Holder
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UPN-J Holder Joint
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UST-1 Solid Universal Joint
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UST-2 Solid Universal Joint
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UST-3 Solid Universal Joint
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UST-3A Joint Attachment
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WR-6 Three-axis Water Hydraulic Micromanipulator
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X 4 Rotating X Block
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YOU 2 Manipulator Set
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YOU 3 Manipulator Set
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YOU Compact Manipulators
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YOU Standard Series Pipette Holders
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